changes in low density lipoprotein susceptibility to oxidation under the exposures of ac magnetic fields in vitro
نویسندگان
چکیده
منابع مشابه
EFFECTS OF UBIQUINOL-1 0 AND f3-CAROTENE ON THE IN VITRO SUSCEPTIBILITY OF LOW-DENSITY LIPOPROTEIN TO COPPER-INDUCED OXIDATION
ABSTRACT Background: Dietary antioxidant intake has been reported to be inversely associated with coronary miery disease. To clarify the possible role oflipophilic antioxidants in the prevention of atherosclerosis, we investigated the effects ofubiquinol-1 0 and ~-carotene on the susceptibility oflow-density lipoprotein(LD L) to oxidative modification. Methods: In this study, first "u...
متن کاملComparative Effects of Copper, Iron, Vanadium and Titanium on Low Density Lipoprotein Oxidation in vitro
Oxidation of low density lipoprotein (LDL) has been strongly implicated in the phathogenesis of atherosclerosis. The use of oxidants in dietary food stuff may lead to the production of oxidized LDL and may increase both the development and the progression of atherosclerosis. The present work investigated the effects of some elements including: copper (Cu), iron (Fe), vanadium (V) and titanium (...
متن کاملEnhanced susceptibility to in vitro oxidation of the dense low density lipoprotein subfraction in healthy subjects.
Oxidative modification of low density lipoprotein (LDL) has been implicated as a factor in the generation of macrophage-derived foam cells, the hallmark of atherosclerotic plaques. Because LDL consists of discrete subfractions with different physicochemical characteristics, the question arises as to whether these LDL subfractions differ in their susceptibility to oxidative modification. To answ...
متن کاملLipid peroxidation and susceptibility of low-density lipoprotein to in vitro oxidation in hyperhomocysteinaemia.
The pathobiochemical mechanism of arteriosclerosis in hyperhomocysteinaemia has not yet been elucidated. In vitro studies have shown that the cytotoxic properties of homocysteine can be ascribed to its generation of reactive oxygen species. We studied lipid peroxidation, both in vivo and in vitro, in 10 homozygous cystathionine synthase-deficient (CSD) patients and in a control group of 10 heal...
متن کاملLow-density lipoprotein susceptibility to in vitro oxidation in healthy smokers and nonsmokers.
We analyzed the susceptibility of low-density lipoproteins (LDL) to oxidation in 17 healthy smokers (43.3 +/- 16.8 pack-years) and 19 healthy nonsmokers, matched for age (smokers: 52 +/- 7 years; nonsmokers: 53 +/- 7 years), gender, and relative body mass. Cholesterol, triglycerides, LDL cholesterol, HDL cholesterol, and apolipoprotein (apo) B were not different between smokers and nonsmokers; ...
متن کاملEffect of Lycopene on Formation of Low Density Lipoprotein-Copper Complex in Copper Catalyzed Peroxidation of Low Density Lipoprotein, as in vitro Experiment
Background: A great deal of evidence has indicated that oxidatively modified LDL plays a critical role in the initiation and progression of atherosclerosis. Antioxidants that can prevent LDL oxidation may act as antiatherogens. Copper is a candidate for oxidizing LDL in atherosclerotic lesions. The binding of copper ions to LDL is usually thought to be a prerequisite for LDL oxidation by copper...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
research in pharmaceutical sciencesجلد ۷، شماره ۵، صفحات ۰-۰
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023